A Renfe high-speed train struck a stopped Iryo train from behind on the Madrid–Andalusia line on Wednesday morning, leaving at least 68 people dead in one of the worst rail accidents in Spain's recent history.

The collision happened at about 8:54 a.m. near kilometer marker 118, close to Urda station in Toledo province. A Renfe AVE (service 2080), carrying about 380 passengers, ran into the back of an Iryo train (service 6076) with more than 170 people aboard. Both were Madrid–Seville services. The impact destroyed several rear cars of the Iryo train, and at least two derailed and fell down an adjacent embankment.

Castilla-La Mancha regional president Emiliano GarcĂ­a-Page gave the provisional toll of at least 68 dead and warned that it could rise because rescuers were struggling to reach the wreckage. More than 50 people were hospitalized in serious or critical condition and taken to hospitals in Castilla-La Mancha and Madrid.

Hundreds of emergency workers took part in the rescue, including about 200 soldiers from Spain's Military Emergencies Unit (UME) with search dogs and heavy machinery. All traffic on the Madrid–Andalusia high-speed corridor was suspended. Both operators set up phone lines for relatives, and the government declared three days of official mourning.

Early indications on the cause. According to the Transport Ministry's first assessment, a failure in the line's LZB signaling and train-protection system temporarily stopped several trains at around 8:32 a.m., about 20 minutes before the crash. The ministry said Adif's control center at Atocha station later allowed trains to resume moving even though the system was showing a red warning that the Iryo train was still occupying the track. Transport Minister Óscar Puente called that decision "inexplicable." Prime Minister Pedro Sánchez promised to go "all the way" in the investigation. These points are unconfirmed. The Railway Accident Investigation Commission (CIAF), working with the Guardia Civil's forensic unit, is examining the event recorders ("black boxes") and Adif's automatic logs. The Guardia Civil has questioned the Adif controller who was managing traffic on that section. The CIAF has not published a report, which usually takes weeks or months.